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Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells

2012; Oxford University Press; Volume: 4; Issue: 4 Linguagem: Inglês

10.1039/c2ib00150k

1757-9708

Florian Rehfeldt, André EX Brown, Matthew Raab, Shenshen Cai, Allison L. Zajac, A. Zemel, Dennis E. Discher,

Planarian Biology and Electrostimulation

Journal Article Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells Get access Florian Rehfeldt, Florian Rehfeldt Biophysical Eng'g. Lab, University of Pennsylvania, Philadelphia 19104, PA, USA. Tel: +1 215 898 48093rd Institute of Physics-Biophysics, Georg-August-University, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany. Fax: +49 551 397720; Tel: +49 551 3913831 E-mail: rehfeldt@physik3.gwdg.de Search for other works by this author on: Oxford Academic Google Scholar André E. X. Brown, André E. X. Brown Biophysical Eng'g. Lab, University of Pennsylvania, Philadelphia 19104, PA, USA. Tel: +1 215 898 4809 Search for other works by this author on: Oxford Academic Google Scholar Matthew Raab, Matthew Raab Biophysical Eng'g. Lab, University of Pennsylvania, Philadelphia 19104, PA, USA. Tel: +1 215 898 4809 Search for other works by this author on: Oxford Academic Google Scholar Shenshen Cai, Shenshen Cai Biophysical Eng'g. Lab, University of Pennsylvania, Philadelphia 19104, PA, USA. Tel: +1 215 898 4809 Search for other works by this author on: Oxford Academic Google Scholar Allison L. Zajac, Allison L. Zajac Biophysical Eng'g. Lab, University of Pennsylvania, Philadelphia 19104, PA, USA. Tel: +1 215 898 4809 Search for other works by this author on: Oxford Academic Google Scholar Assaf Zemel, Assaf Zemel Institute of Dental Sciences, Faculty of Dental Medicine, and the Fritz Haber Center for Molecular Dynamics, the Hebrew University-Hadassah Medical Center, Jerusalem 91120, Israel Search for other works by this author on: Oxford Academic Google Scholar Dennis E. Discher Dennis E. Discher Biophysical Eng'g. Lab, University of Pennsylvania, Philadelphia 19104, PA, USA. Tel: +1 215 898 4809 E-mail: discher@seas.upenn.edu Search for other works by this author on: Oxford Academic Google Scholar Integrative Biology, Volume 4, Issue 4, April 2012, Pages 422–430, https://doi.org/10.1039/c2ib00150k Published: 20 February 2012 Article history Received: 31 October 2011 Accepted: 12 January 2012 Published: 20 February 2012