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PhyloBayes 3: a Bayesian software package for phylogenetic reconstruction and molecular dating

2009; Oxford University Press; Volume: 25; Issue: 17 Linguagem: Inglês

10.1093/bioinformatics/btp368

1367-4811

Nicolas Lartillot, Thomas Lepage, Samuel Blanquart,

Archaeology and ancient environmental studies

Abstract Motivation: A variety of probabilistic models describing the evolution of DNA or protein sequences have been proposed for phylogenetic reconstruction or for molecular dating. However, there still lacks a common implementation allowing one to freely combine these independent features, so as to test their ability to jointly improve phylogenetic and dating accuracy. Results: We propose a software package, PhyloBayes 3, which can be used for conducting Bayesian phylogenetic reconstruction and molecular dating analyses, using a large variety of amino acid replacement and nucleotide substitution models, including empirical mixtures or non-parametric models, as well as alternative clock relaxation processes. Availability: PhyloBayes is freely available from our web site http://www.phylobayes.org. It works under Linux, Mac OsX and Windows operating systems. Contact: nicolas.lartillot@umontreal.ca Supplementary information: Supplementary data are available at Bioinformatics online.