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Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

2013; American Association for the Advancement of Science; Volume: 5; Issue: 185 Linguagem: Inglês

10.1126/scitranslmed.3006368

1946-6242

Philip R. Dormitzer, Pirada Suphaphiphat, Daniel G. Gibson, David E. Wentworth, Timothy B. Stockwell, Mikkel A. Algire, Nina Alperovich, Mario Barro, David Brown, Stewart Craig, Brian M. Dattilo, Evgeniya A. Denisova, Ivna De Souza, Markus Eickmann, Vivien G. Dugan, Annette Ferrari, Raul Gomila, Liqun Han, Casey Judge, Sarthak Mane, Mikhail Matrosovich, Chuck Merryman, Giuseppe Palladino, Gene A. Palmer, Terika Spencer, Thomas Strecker, Heidi Trusheim, Jennifer Uhlendorff, Yingxia Wen, Anthony Yee, Jayshree Zaveri, Bin Zhou, Stephan Becker, Armen Donabedian, Peter W. Mason, John I. Glass, Rino Rappuoli, J. Craig Venter,

Respiratory viral infections research

Synthesis of viral genes from sequence information allows rapid generation of influenza vaccine viruses, facilitating rapid responses to influenza pandemics.