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Editorial Revisado por pares
BIBTEX RIS

EDITORIAL REVIEW: MECHANISMS OF AMINOGLYCOSIDE NEPHROTOXICITY

1989; Wiley; Volume: 16; Issue: 1 Linguagem: Inglês

10.1111/j.1440-1681.1989.tb01901.x

ISSN

1440-1681

Autores

William M. Bennett,

Tópico(s)

Poisoning and overdose treatments

Resumo

SUMMARY Aminoglycosides continue to be widely used for the treatment of serious Gram‐negative infections. Ten to fifteen per cent of all courses of therapy are complicated by declines in renal function, despite close monitoring of serum drug levels. The proposed pathogenesis and biochemical mechanisms of renal dysfunction caused by these commonly used therapeutic agents are discussed.

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