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Base- and Ligand-free Room-Temperature Synthesis of N-Fused Heteroaromatic Compounds via the Transition Metal-Catalyzed Cycloisomerization Protocol

2007; American Chemical Society; Volume: 9; Issue: 17 Linguagem: Inglês

10.1021/ol701464j

1523-7060

И. В. Серегин, Alex W. Schammel, Vladimir Gevorgyan,

Catalytic C–H Functionalization Methods

A new practical method for the synthesis of N-fused heterocycles via the transition metal-catalyzed cycloisomerization of heterocyles possessing a propagyl group has been developed. This very mild, base- and ligand-free method allows for the synthesis of diverse fused heterocyclic cores in good to excellent yields.