Acneiform Papules on the Neck
1995; American Medical Association; Volume: 131; Issue: 3 Linguagem: Inglês
10.1001/archderm.1995.01690150105021
ISSN1538-3652
Autores Tópico(s)Skin and Cellular Biology Research
ResumoREPORT OF A CASE In 1975, a 29-year-old white woman was diagnosed with Wilson's disease by neurologic examination and the presence of Kayser-Fleischer rings. She was given penicillamine (0.5 mg twice daily), which reversed most of her symptoms, and the Kayser-Fleischer rings disappeared. Approximately 14 years later, an acneiform eruption developed on her neck that persisted for 1 year. Physical examination revealed erythematous papules in an arciform pattern on the anterior neck ( Figure 1 ). A lesional skin specimen was obtained and submitted for histopathologic examination ( Figures 2 through 4 ). These lesions failed to respond to intralesional triamcinolone acetonide but later improved with liquid nitrogen cryotherapy. What is your diagnosis? DIAGNOSIS: Elastosis perforans serpiginosa (EPS). HISTOPATHOLOGIC FINDING Individual papules consisted of a reactive thickened epidermis, increased dermal elastin, and inflammation. The epidermis was hyperkeratotic and acanthotic. Occasionally, the epidermis was disrupted by transepidermal
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