Simultaneous MR/PET Imaging of the Human Brain: Feasibility Study
2008; Radiological Society of North America; Volume: 248; Issue: 3 Linguagem: Inglês
10.1148/radiol.2483071927
ISSN1527-1315
AutoresHeinz-Peter Schlemmer, Bernd J. Pichler, M. Schmand, Z. Burbar, Christian Michel, Ralf Ladebeck, Kirstin Jattke, David W. Townsend, Claude Nahmias, Pradeep K. Jacob, Wolf-Dieter Heiss, Claus D. Claussen,
Tópico(s)Atomic and Subatomic Physics Research
ResumoThe purpose of this study was to apply a magnetic resonance (MR) imaging-compatible positron emission tomographic (PET) detector technology for simultaneous MR/PET imaging of the human brain and skull base. The PET detector ring consists of lutetium oxyorthosilicate (LSO) scintillation crystals in combination with avalanche photodiodes (APDs) mounted in a clinical 3-T MR imager with use of the birdcage transmit/receive head coil. Following phantom studies, two patients were simultaneously examined by using fluorine 18 fluorodeoxyglucose (FDG) PET and MR imaging and spectroscopy. MR/PET data enabled accurate coregistration of morphologic and multifunctional information. Simultaneous MR/PET imaging is feasible in humans, opening up new possibilities for the emerging field of molecular imaging.
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