Portal de Periódicos da CAPES

Molecular radiation biology: Perspectives for radiation oncology

2009; Elsevier BV; Volume: 92; Issue: 3 Linguagem: Inglês

10.1016/j.radonc.2009.08.023

1879-0887

H. Peter Rodemann,

Effects of Radiation Exposure

Molecular radiation biology has become a powerful discipline and tool for detailed investigations into biological mechanisms of problems and aspects of modern radiation oncology. In this context special emphasis is given to the mechanisms of DNA-repair and their relevance for radiation therapy, to the relevance of radiation-induced signal transduction for normal and tumour cell response, to the role of the micro-environment for the modification of tumour as well as normal tissue responses to radiation, and last but not the least to the aspects of individualization and molecular targeting in radiation therapy. These topics were extensively discussed during the 11th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, which was held at the Wolfsberg Conference Center in Ermatingen, Switzerland, from June 27 to 29, 2009. About 160 basic, preclinical and clinical scientists from 21 countries worldwide participated in this 2009-edition of the Wolfsberg Meeting Series on Molecular Radiation Biology/Oncology to discuss cutting-edge research in the above-mentioned topics. In the following some of the major achievements, which have been made over the recent years in the fields of basic and clinically oriented research in radiation biology as well as experimental and translational radiation oncology will be reviewed.