Portal de Periódicos da CAPES

Serotype Distribution of Invasive Group B Streptococcal Isolates in Infants: Results from a Nationwide Active Laboratory Surveillance Study over 2 Years in Germany

2005; Oxford University Press; Volume: 40; Issue: 5 Linguagem: Inglês

10.1086/427942

1537-6591

Kirsten Fluegge, Sven Supper, Anette Siedler, Reinhard Berner,

Pneumonia and Respiratory Infections

We report the serotype distribution of invasive group B streptococci (GBS) isolated from 296 infants in Germany. Serotype distribution was as follows: serotype Ia, 15%; Ib, 5%; II, 5%; III, 65%; IV, 1%; and V, 8%. Analysis of serotype according to the source of isolation highlighted the considerable role of serotype III in meningitis in early-onset infection (82%) and late-onset infection (84%). Use of a trivalent GBS vaccine in Germany could theoretically provide protection against 84% and 94% of invasive early-onset and late-onset infections, respectively.