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The Effect of Contact Force in Atrial Radiofrequency Ablation

2015; Elsevier BV; Volume: 1; Issue: 5 Linguagem: Inglês

10.1016/j.jacep.2015.06.003

2405-5018

Steven E. Williams, James Harrison, Henry Chubb, Lars Bloch, Niels Peter Andersen, Høgni Dam, Rashed Karim, John Whitaker, Jaswinder Gill, Michael Cooklin, Christopher A. Rinaldi, Kawal Rhode, Matthew Wright, Tobias Schaeffter, Won Yong Kim, Henrik Kjærulf Jensen, Reza Razavi, Mark O’Neill,

Cardiovascular Function and Risk Factors

This study sought to determine the effect of contact force (CF) on atrial lesion size, quality, and transmurality by using a chronic porcine model of radiofrequency ablation.CF is a major determinant of ventricular lesion formation, but uncertainty exists regarding the most appropriate CF parameters to safely achieve permanent, transmural lesions in the atria.Intercaval linear ablation (30 W, 42°C, 17 ml/min irrigation) was performed in 8 Göttingen minipigs by using a force-sensing catheter with CF >20 g (high force) or 20 g) resulted in more acute tissue edema than low CF (<10 g), chronically there was no difference in lesion size, quality, or transmurality. Appropriate CF targets for atrial ablation may be lower than previously thought.