Interaction between Posaconazole and Caspofungin in Concomitant Treatment of Mice with Systemic Aspergillus Infection
2006; American Society for Microbiology; Volume: 50; Issue: 7 Linguagem: Inglês
10.1128/aac.00829-05
ISSN1098-6596
AutoresAnthony Cacciapuoti, Judith Halpern, Cara Mendrick, Christine Norris, Reena Patel, David Loebenberg,
Tópico(s)Infectious Diseases and Mycology
ResumoThe interaction of posaconazole and caspofungin was evaluated in concomitant treatment of Aspergillus fumigatus (two strains) or A. flavus (one strain) systemic infections in immunocompetent mice. Survival curves for mice treated with the combinations were compared statistically with those for mice treated with the component monotherapies. No antagonism was observed.
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