Dermal reactivity to histamine, serotonin and bradykinin in relation to allergic skin reactions of the horse
1986; Wiley; Volume: 9; Issue: 1 Linguagem: Inglês
10.1111/j.1365-2885.1986.tb00010.x
ISSN1365-2885
AutoresA. N. Morrow, P.J. Quinn, K. P. Baker,
Tópico(s)Entomological Studies and Ecology
ResumoThe reactivity of horse skin to intradermal inoculation of histamine, serotonin and bradykinin was investigated, and the resulting reactions compared with those produced in the same horses by a 1% whole‐body extract of Cnliroides. Both histamine and bradykinin produced large reactions, but there was no significant correlation between the dermal responsiveness to insect allergen and either histamine or bradykinin. Two anti‐hislamine drugs (promethazine hydrochloride and tripelennaniine hydrochloride) were effective in reducing the reaction produced by the insect extract.
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