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Leukemia in Man Following Exposure to Ionizing Radiation

1962; American College of Physicians; Volume: 56; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-56-4-590

1539-3704

A.B. Brill,

Carcinogens and Genotoxicity Assessment

Article1 April 1962Leukemia in Man Following Exposure to Ionizing RadiationA Summary of the Findings in Hiroshima and Nagasaki, and a Comparison with Other Human ExperienceA. BERTRAND BRILL, M.D., PH.D., MASANOBU TOMONAGA, M.D., ROBERT M. HEYSSEL, M.D.A. BERTRAND BRILL, M.D., PH.D.Search for more papers by this author, MASANOBU TOMONAGA, M.D.Search for more papers by this author, ROBERT M. HEYSSEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-56-4-590 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe occurrence of leukemia in an individual with a history of previous exposure to ionizing radiation was first noted in 1911. Between that year and 1939 a total of 18 cases was reported, and leukemia was considered an occupational risk of radiologists (1-7). More recent studies have confirmed these observations (8-14). An increased incidence of leukemia has subsequently been described in such diverse groups as children who have been exposedin uteroto X irradiation during diagnostic pelvimetry of the mother (15-21), children who were treated with X rays as infants for enlargement of the thymus gland (22-29), adults with...References1. BERNARDBOIRONCORNU JMP: Remarques sur l'hématologie des radioleucoses humaines. Sang 29: 734, 1958. Google Scholar2. LABORDELECLERCQ SJ: Les maladies professionnelles causées par les rayons X et les substances radioactives. Echo Med. Nord 6: 765, 1936. Google Scholar3. MARCH HC: Leukemia in radiologists. Radiology 43: 275, 1944. CrossrefGoogle Scholar4. HENSHAWHAWKINS PSJW: Incidence of leukemia in physicians. J. Nat. Cancer Inst. 4: 339, 1944. Google Scholar5. ULRICH H: Incidence of leukemia in radiologists. New Engl. J. Med. 234: 45, 1946. CrossrefMedlineGoogle Scholar6. DUBLINSPIEGELMAN LIM: The longevity and mortality of American physicians, 1938-1942. J. A. M. 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Author, Article, and Disclosure InformationAffiliations: Hiroshima-Nagasaki,From the Atomic Bomb Casualty Commission, Hiroshima-Nagasaki, Japan, a research agency of the United States National Academy of Sciences-National Research Council.Supported by a grant from the United States Atomic Energy Commission administered in cooperation with the Japanese National Institute of Health of the Ministry of Health and Welfare.Requests for reprints should be addressed to the Librarian, Atomic Bomb Casualty Commission, Hiroshima, Japan. 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SANDBERG, M.D.Delayed Radiation Effects in Atomic-Bomb SurvivorsFactors Relating to the Application of Radioisotopes to Circulatory Support SystemsReflections on Some Recent Progress in Human RadiobiologyPerspectives in The Epidemiology Of LeukemiaThe relative sensitivity of different tissues to tumour induction by radiation: The human evidenceFollow-up Study of Patients Treated by X-ray Epilation for Tinea CapitisEpidemiological findings and electron microscopic observations in human leukemia and canine contactsREFERENCESCarcinogenic Risk from Ionizing Radiations Used for Diagnostic PurposeNeoplasms in youthful populations following X-ray treatment in infancyRadiogenic lung cancer in man: Exposure-effect relationshipThe location and relative numbers of rediosensitive cells and of cells not considered to be rediosensitive in bone and in bone marrowThe location and relative numbers of rediosensitive cells and of cells not considered to be rediosensitive in bone and in bone marrowFREE RADICALS AND HEALTH: INDICATORS FOR A UNIFYING CONCEPTEnvironmental HazardsHuman Effects of Chronic, Low Dose RadiationRelation between Cancer and Congenital Defects in ManRadiation-Related Leukemia in Hiroshima and Nagasaki, 1946–1964The Changing Pattern of Cancer Morbidity and Mortality and Its ImplicationsUnifying Concept of the Origin of CancerEtiology of Childhood Leukemia: Epidemiologic EvidenceMortality in California veterinariansLeukemia in man and MousePhänomenologie der Strahlenwirkungen auf Organe und OrgansystemeSpätschäden nach ThorotrastanwendungEffects of ionizing radiation in childrenRadiation as the Cause of Lung Cancer among Uranium MinersChapter I introductionChapter I introductionAn Appraisal of the Current Fall-Out Levels and their Biological SignificanceAn epidemiological study of childhood leukemiaSerial cytogenetic and hematologic studies on amongol with trisomy-21 and acute congenital leukemiaLEUKÆMOGENIC EFFECT OF IONISING-IRRADIATION TREATMENT IN POLYCYTHÆMIARadiation, Chromosomes and Viruses in the Etiology of LeukemiaUnusual Forms and Aspects of Cancer in ManMYELOID LEUKEMIA IN THE MOUSEWar and the Living EnvironmentDown's Syndrome (Mongolism), Other Congenital Malformations and Cancers among the Sibs of Leukemic Children 1 April 1962Volume 56, Issue 4Page: 590-609KeywordsChildrenInfantsIonizing radiationRadiologistsResearch laboratoriesRisk managementScientistsThymus Issue Published: 1 April 1962 PDF DownloadLoading ...