Cobalt-Catalyzed Aziridination with Diphenylphosphoryl Azide (DPPA): Direct Synthesis of N -Phosphorus-Substituted Aziridines from Alkenes
2006; American Chemical Society; Volume: 71; Issue: 17 Linguagem: Inglês
10.1021/jo0609226
ISSN1520-6904
AutoresGuang‐Yao Gao, Jess E. Jones, Renu Vyas, Jeremiah D. Harden, X. Peter Zhang,
Tópico(s)Sulfur-Based Synthesis Techniques
ResumoA new catalytic aziridination system that consists of cobalt(II) tetraphenylporphyrin [Co(TPP)] as the catalyst and diphenylphosphoryl azide (DPPA) as the nitrene source has been developed. The cobalt-based catalytic system allows direct synthesis of N-phosphorus-substituted aziridines from alkenes with dinitrogen as the byproduct. Cobalt ion seems essential to the catalytic aziridination with DPPA as no or only trace amounts of the desired products were observed with other metal complexes of tetraphenylporphyrin.
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