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BIBTEX RIS

Serodiagnosis of Chronic and Acute Chagas' Disease with Trypanosoma cruzi Recombinant Proteins: Results of a Collaborative Study in Six Latin American Countries

2004; American Society for Microbiology; Volume: 42; Issue: 1 Linguagem: Inglês

10.1128/jcm.42.1.449-452.2004

ISSN

1098-660X

Autores

Eufrosina Setsu Umezawa, Alejandro O. Luquetti, Gabriela Levitus, Carlos Ponce, Elisa Ponce, Diana Henríquez, Susana Revollo, Bertha Espinoza, Octávio E. Sousa, Baldip Khan, José Franco da Silveira,

Tópico(s)

Research on Leishmaniasis Studies

Resumo

ABSTRACT An enzyme-linked immunosorbent assay to diagnose Chagas' disease by a serological test was performed with Trypanosoma cruzi recombinant antigens (JL8, MAP, and TcPo). High sensitivity (99.4%) and specificity (99.3%) were obtained when JL8 was combined with MAP (JM) and tested with 150 serum samples from chagasic and 142 nonchagasic individuals. Moreover, JM also diagnosed 84.2% of patients in the acute phase of T. cruzi infection.

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