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Leishmaniasis Recidivans Recurrence after 43 Years: A Clinical and Immunologic Report after Successful Treatment

2001; Oxford University Press; Volume: 33; Issue: 7 Linguagem: Inglês

10.1086/322643

1537-6591

Mary Marovich, Rosalía Lira, Marc Shepard, Glenn H. Fuchs, Richard Kruetzer, Thomas B. Nutman, Franklin A. Neva,

Urticaria and Related Conditions

We describe a patient with very late recurring leishmaniasis recidivans from whom lesional biopsy samples were obtained during and after topical steroid treatment that demonstrated the ability of the host to contain the parasite in the absence of therapy. Combination therapy with intralesional sodium stibogluconate and oral itraconazole was successful and immunologic data suggest that both CD4+ and CD8+ T cell subsets had roles in this disease process.