Heparin‐Coated Gold Nanoparticles for Liver‐Specific CT Imaging
2009; Wiley; Volume: 15; Issue: 48 Linguagem: Inglês
10.1002/chem.200902344
ISSN1521-3765
AutoresIn‐Cheol Sun, Dae‐Kyung Eun, Jin Hee Na, Seulki Lee, Il‐Jin Kim, Inchan Youn, Chang‐Yong Ko, Han‐Sung Kim, Dohyung Lim, Kuiwon Choi, Phillip B. Messersmith, Tae Gwan Park, Sang Yoon Kim, Ick Chan Kwon, Kwangmeyung Kim, Cheol‐Hee Ahn,
Tópico(s)Catalytic Processes in Materials Science
ResumoChemistry – A European JournalVolume 15, Issue 48 p. 13341-13347 Communication Heparin-Coated Gold Nanoparticles for Liver-Specific CT Imaging In-Cheol Sun, In-Cheol Sun Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorDae-Kyung Eun, Dae-Kyung Eun Research Institute of Advanced Materials (RIAM), Department of Materials Science and Engineering, Seoul National University, San 56-1, Sillim, Gwanak, Seoul, 151-744 (Korea), Fax: (+82)2-883-8197Search for more papers by this authorJin Hee Na, Jin Hee Na Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorSeulki Lee Dr., Seulki Lee Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorIl-Jin Kim, Il-Jin Kim Department of Chemistry, College of Science, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-791 (Korea)Search for more papers by this authorIn-Chan Youn Dr., In-Chan Youn Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorChang-Yong Ko Dr., Chang-Yong Ko Dr. Department of Biomedical Engineering, Yonsei University, Wonju, Ganwondo, 220-710 (Korea)Search for more papers by this authorHan-Sung Kim Dr., Han-Sung Kim Dr. Department of Biomedical Engineering, Yonsei University, Wonju, Ganwondo, 220-710 (Korea)Search for more papers by this authorDohyung Lim Dr., Dohyung Lim Dr. Silver Technology Center, Korea Institute of Industrial Technology, 35-5 Hongcheon, Ipjang, Cheonan, Chungnam (Korea)Search for more papers by this authorKuiwon Choi Dr., Kuiwon Choi Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorPhillip B. Messersmith Dr., Phillip B. Messersmith Dr. Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanstron, IL 60208 (USA)Search for more papers by this authorTae Gwan Park Dr., Tae Gwan Park Dr. Department of Biological Sciences, Korea Advanced Institute of Science Technology, Daejeon 305-701 (Korea)Search for more papers by this authorSang Yoon Kim Dr., Sang Yoon Kim Dr. Department of Otolaryngology-Head and Neck Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736 (South Korea)Search for more papers by this authorIck Chan Kwon Dr., Ick Chan Kwon Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorKwangmeyung Kim Dr., Kwangmeyung Kim Dr. kim@kist.re.kr Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorCheol-Hee Ahn Dr., Cheol-Hee Ahn Dr. chahn@snu.ac.kr Research Institute of Advanced Materials (RIAM), Department of Materials Science and Engineering, Seoul National University, San 56-1, Sillim, Gwanak, Seoul, 151-744 (Korea), Fax: (+82)2-883-8197Search for more papers by this author In-Cheol Sun, In-Cheol Sun Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorDae-Kyung Eun, Dae-Kyung Eun Research Institute of Advanced Materials (RIAM), Department of Materials Science and Engineering, Seoul National University, San 56-1, Sillim, Gwanak, Seoul, 151-744 (Korea), Fax: (+82)2-883-8197Search for more papers by this authorJin Hee Na, Jin Hee Na Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorSeulki Lee Dr., Seulki Lee Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorIl-Jin Kim, Il-Jin Kim Department of Chemistry, College of Science, Korea University, Anam-dong, Seongbuk-gu, Seoul 136-791 (Korea)Search for more papers by this authorIn-Chan Youn Dr., In-Chan Youn Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorChang-Yong Ko Dr., Chang-Yong Ko Dr. Department of Biomedical Engineering, Yonsei University, Wonju, Ganwondo, 220-710 (Korea)Search for more papers by this authorHan-Sung Kim Dr., Han-Sung Kim Dr. Department of Biomedical Engineering, Yonsei University, Wonju, Ganwondo, 220-710 (Korea)Search for more papers by this authorDohyung Lim Dr., Dohyung Lim Dr. Silver Technology Center, Korea Institute of Industrial Technology, 35-5 Hongcheon, Ipjang, Cheonan, Chungnam (Korea)Search for more papers by this authorKuiwon Choi Dr., Kuiwon Choi Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorPhillip B. Messersmith Dr., Phillip B. Messersmith Dr. Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanstron, IL 60208 (USA)Search for more papers by this authorTae Gwan Park Dr., Tae Gwan Park Dr. Department of Biological Sciences, Korea Advanced Institute of Science Technology, Daejeon 305-701 (Korea)Search for more papers by this authorSang Yoon Kim Dr., Sang Yoon Kim Dr. Department of Otolaryngology-Head and Neck Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul 138-736 (South Korea)Search for more papers by this authorIck Chan Kwon Dr., Ick Chan Kwon Dr. Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorKwangmeyung Kim Dr., Kwangmeyung Kim Dr. kim@kist.re.kr Biomedical Research Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul, 136-791 (Korea), Fax: (+82) 2-958-5909Search for more papers by this authorCheol-Hee Ahn Dr., Cheol-Hee Ahn Dr. chahn@snu.ac.kr Research Institute of Advanced Materials (RIAM), Department of Materials Science and Engineering, Seoul National University, San 56-1, Sillim, Gwanak, Seoul, 151-744 (Korea), Fax: (+82)2-883-8197Search for more papers by this author First published: 08 December 2009 https://doi.org/10.1002/chem.200902344Citations: 126Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Gold nanoprobe: Heparin–DOPA-coated gold nanoparticles (HEPA–AuNPs) showed low toxicity, prolonged stability, and an enhanced X-ray absorption coefficient in vitro. In vivo microCT images showed that HEPA–AuNPs produced enhanced liver-specific CT images compared with iodine-based contrast agents, thus highlighting its potential as a novel, liver-specific CT imaging agent (see figure). Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description chem_200902344_sm_miscellaneous_information.pdf1.8 MB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume15, Issue48December 14, 2009Pages 13341-13347 RelatedInformation
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