Morphological and cytochemical characteristics of leukaemic promyelocytes
2003; Elsevier BV; Volume: 16; Issue: 3 Linguagem: Inglês
10.1016/s1521-6926(03)00061-6
ISSN1532-1924
AutoresVincenzo Liso, John M. Bennett,
Tópico(s)Antioxidant Activity and Oxidative Stress
ResumoEvaluation of cell morphology is usually sufficient to diagnose acute promyelocytic leukaemia (APL). In this chapter we discuss the features of classical hypergranular APL, the APL variant, hyperbasophilic promyelocytic leukaemia, APL with basophil-like granules, acute eosinophilic leukaemia with PML/RARα positivity and the morphology of APL cells lacking t(15;17). In addition to morphological examination, cytochemical investigations (peroxidase chloroacetate-esterase, etc.) may help further in defining the cytology of leukaemic cells in APL.
Referência(s)