Laser scanning confocal endomicroscopy in the neurosurgical operating room: a review and discussion of future applications
2014; American Association of Neurological Surgeons; Volume: 36; Issue: 2 Linguagem: Inglês
10.3171/2013.11.focus13484
ISSN1092-0684
AutoresMichael A. Mooney, Aqib Zehri, Joseph Georges, Peter Nakaji,
Tópico(s)Medical Imaging Techniques and Applications
ResumoLaser scanning confocal endomicroscopy (LSCE) is an emerging technology for examining brain neoplasms in vivo. While great advances have been made in macroscopic fluorescence in recent years, the ability to perform confocal microscopy in vivo expands the potential of fluorescent tumor labeling, can improve intraoperative tissue diagnosis, and provides real-time guidance for tumor resection intraoperatively. In this review, the authors highlight the technical aspects of confocal endomicroscopy and fluorophores relevant to the neurosurgeon, provide a comprehensive summary of LSCE in animal and human neurosurgical studies to date, and discuss the future directions and potential for LSCE in neurosurgery.
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