Portal de Periódicos da CAPES

The presence of heparan sulfate in the mammalian oocyte provides a clue to human sperm nuclear decondensation in vivo

2008; Oxford University Press; Volume: 23; Issue: 5 Linguagem: Inglês

10.1093/humrep/den028

1460-2350

Marina Romanato, Vanina Laura Julianelli, M. Zappi, Lucrecia Calvo, Juan Carlos Calvo,

Proteoglycans and glycosaminoglycans research

BACKGROUNDPrevious results from our laboratory have led us to propose heparan sulfate (HS) as a putative protamine acceptor during human sperm decondensation in vivo. The aim of this paper was to investigate the presence of glycosaminoglycans in the mammalian oocyte in an effort to better support this contention.