A comparative study of antithrombotic and antiplatelet activities of different fucoidans from Laminaria japonica
2011; Elsevier BV; Volume: 129; Issue: 6 Linguagem: Inglês
10.1016/j.thromres.2011.07.041
ISSN1879-2472
AutoresXue Zhao, Dong Shizhu, Jingfeng Wang, Fang Li, Anjin Chen, Bafang Li,
Tópico(s)Algal biology and biofuel production
ResumoFucoidans extracted from brown algae represent an intriguing group of natural fucose-enriched sulfated polysaccharide, with excellent anticoagulant, antimetastatic, antiangiogenic and anti-inflammatory activities. In the present study, we compared antithrombotic activities of four fucoidan fractions with different molecular weight and sulfated ester content from Laminaria japonica in an electrical induced arterial thrombosis and their potential mechanism underlying such activity.
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