The Influence of 5-Hydroxytryptamine (Serotonin) on Blood Flow in the Dog Pulp
1986; SAGE Publishing; Volume: 65; Issue: 5 Linguagem: Inglês
10.1177/00220345860650051001
ISSN1544-0591
AutoresSungpyo Kim, Henry O. Trowbridge, J. Dörscher-Kim,
Tópico(s)Pharmacological Effects and Assays
ResumoThe effect of intra-arterial injection of 5-hydroxytryptamine (5-HT) on pulpal blood flow of the dog was determined using the 15-μm radioisotope-labeled microsphere injection method. Pulpal blood flow was significantly reduced following the 5-HT injection. This decrease in blood flow appeared to be due to vasoconstriction as determined by an increase in pulpal vascular hindrance. However, our findings do not preclude the possibility that blood flow was reduced as a result of passive compression of venules produced by vasodilation in a low-compliance environment.
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