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Revisão Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Chronic inflammatory demyelinating polyradiculoneuropathy in chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: case report

2007; Thieme Medical Publishers (Germany); Volume: 65; Issue: 3a Linguagem: Inglês

10.1590/s0004-282x2007000400031

ISSN

1678-4227

Autores

Paulo José Lorenzoni, Rosana Hermínia Scola, Ana Lucila Moreira, Ana Paula Trentin, Hélio A.G. Teive, Ricardo Pasqüini, Lineu César Werneck,

Tópico(s)

Multiple Sclerosis Research Studies

Resumo

The chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an unusual but important complication of hematopoietic stem cell transplantation (HSCT) rarely reported to date. We describe a 17-year-old woman with a diagnosis of acute myeloid leukemia due to Fanconi's anemia who was submitted to allogeneic HSCT and developed CIDP as part of graft-versus-host disease. Investigation showed high cerebrospinal fluid protein; electrophysiological studies revealed sensory-motor demyelinating polyradiculoneuropathy; muscle and nerve biopsy were compatible with CIDP.

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