Produção Nacional
Revisado por pares
Effects of resistance training on resistin, leptin, cytokines, and muscle force in elderly post-menopausal women
2009; Taylor & Francis; Volume: 27; Issue: 14 Linguagem: Inglês
10.1080/02640410903352923
ISSN1466-447X
AutoresJonato Prestes, Gilberto Eiji Shiguemoto, João Paulo Botero, Anelena Bueno Frollini, Rodrigo Dias, Richard Diego Leite, Guilherme Borges Pereira, Rodrigo Ferro Magosso, Vilmar Baldissera, Cláudia Regina Cavaglieri, Sergio Perez,
Tópico(s)Adipose Tissue and Metabolism
ResumoAbstract It may be that resistance exercise can be used to prevent the degenerative processes and inflammation associated with ageing. Thus, the aim of the present study was to evaluate the effects of resistance training on cytokines, leptin, resistin, and muscle strength in post-menopausal women. Thirty-five sedentary women (mean age 63.18 years, s = 4.8; height 1.64 m, s = 0.07; body mass 57.84 kg, s = 7.70) were recruited. The 16 weeks of periodized resistance training consisted of two weekly sessions of three sets of 6–14 repetition maximum. Maximal strength was tested in bench press, 45° leg press, and arm curl. Plasma tumour necrosis factor-α, interleukin-6, interleukin-15, leptin, and resistin were determined by enzyme-linked immunosorbent assay. Maximal strength on all measures was increased after 16 weeks. There were minor or no modifications in tumour necrosis factor-α and interleukin-15. Interleukin-6 was decreased 48 h after compared with baseline and declined after 16 weeks. Leptin decreased 24 h after compared with baseline and was reduced at baseline and 48 h after compared with pre-training. There was a decrease in resistin after 24 and 48 h compared with baseline and a decline in baseline and immediately after levels compared with pre-training. A possible explanation of the results of the present study is a lower production of pro-inflammatory cytokines by the innate immune system. Periodized resistance training seems to be an important intervention to reduce systemic inflammation in this population. Keywords: Ageinginflammationsystemic biomarkersresistance training
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