Produção Nacional
Revisado por pares
Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study
2014; BioMed Central; Volume: 9; Issue: 1 Linguagem: Inglês
10.1186/1749-7922-9-37
ISSN1749-7922
AutoresMassimo Sartelli, Fausto Catena, Luca Ansaloni, Federico Coccolini, Davide Corbella, Ernest E. Moore, Mark A. Malangoni, George C. Velmahos, Raúl Coimbra, Kaoru Koike, Ari Leppäniemi, Walter Biffl, Zsolt J. Balogh, Cino Bendinelli, Sanjay Gupta, Yoram Kluger, Ferdinando Agresta, Salomone Di Saverio, Gregorio Tugnoli, Elio Jovine, Carlos A. Ordóñez, James Whelan, Gustavo Pereira Fraga, Carlos Augusto Gomes, Gerson Alves Pereira Júnior, Kuo‐Ching Yuan, Miklosh Bala, Miroslav P. Peev, Offir Ben‐Ishay, Yunfeng Cui, Sanjay Marwah, Sanoop Koshy Zachariah, Imtiaz Wani, Muthukumaran Rangarajan, Boris Sakakushev, Victor Kong, Adamu Ahmed, Ashraf Abbas, Ricardo Alessandro Teixeira Gonsaga, Gianluca Guercioni, Nereo Vettoretto, Elia Poiasina, Rafael Díaz-Nieto, Damien Massalou, M Škrovina, Ihor Gerych, Goran Augustin, Jakub Kenig, Vladimir Khokha, Cristian Tranà, Kenneth Yuh Yen Kok, Alain Chichom‐Mefire, Jae Gil Lee, Suk‐Kyung Hong, Helmut Alfredo Segovia Lohse, Wagih Ghnnam, Alfredo Verni, Varut Lohsiriwat, Boonying Siribumrungwong, Tamer El Zalabany, Alberto Tavares, Gian Luca Baiocchi, Koray Daş, Julien Jarry, M Zida, Norio Sato, Kiyoshi Murata, Tomohisa Shoko, Takayuki Irahara, Ahmed O Hamedelneel, Noel Naidoo, A. R. K. Adesunkanmi, Yoshiro Kobe, Wataru Ishii, Kazuyuki Oka, Yoshimitsu Izawa, Hytham K. S. Hamid, Iqbal Khan, AK Attri, Rajeev Sharma, Juan Sanjuán, Marisol Badiel, Rita Barnabé,
Tópico(s)Amoebic Infections and Treatments
ResumoThe CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a six-month study period (October 2012-March 2013). The study included patients older than 18 years undergoing surgery or interventional drainage to address complicated intra-abdominal infections (IAIs). 1898 patients with a mean age of 51.6 years (range 18-99) were enrolled in the study. 777 patients (41%) were women and 1,121 (59%) were men. Among these patients, 1,645 (86.7%) were affected by community-acquired IAIs while the remaining 253 (13.3%) suffered from healthcare-associated infections. Intraperitoneal specimens were collected from 1,190 (62.7%) of the enrolled patients. 827 patients (43.6%) were affected by generalized peritonitis while 1071 (56.4%) suffered from localized peritonitis or abscesses. The overall mortality rate was 10.5% (199/1898). According to stepwise multivariate analysis (PR = 0.005 and PE = 0.001), several criteria were found to be independent variables predictive of mortality, including patient age (OR = 1.1; 95%CI = 1.0-1.1; p < 0.0001), the presence of small bowel perforation (OR = 2.8; 95%CI = 1.5-5.3; p < 0.0001), a delayed initial intervention (a delay exceeding 24 hours) (OR = 1.8; 95%CI = 1.5-3.7; p < 0.0001), ICU admission (OR = 5.9; 95%CI = 3.6-9.5; p < 0.0001) and patient immunosuppression (OR = 3.8; 95%CI = 2.1-6.7; p < 0.0001).
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