Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential
2014; BioMed Central; Volume: 9; Issue: 1 Linguagem: Inglês
10.1186/1749-8546-9-19
ISSN1991-0150
AutoresKam Lok Wong, Ricky Ngok‐Shun Wong, Liang Zhang, Wing Keung Liu, Tzi Bun Ng, Pang Chui Shaw, Philip Chi Lip Kwok, Yau Ming Lai, Zhang Jin Zhang, Yanbo Zhang, Yao Tong, H. Cheung, Jia Lu, Stephen Cho Wing Sze,
Tópico(s)Biochemical and Structural Characterization
ResumoAbstract Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris , Ganoderma, Momordica cochinchinensis , Viscum album , Poria cocos , Senna obtusifolia , Panax notoginseng , Smilax glabra , Ginkgo biloba , Dioscorea batatas , and Trichosanthes kirilowii . This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines.
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