Artigo Acesso aberto Revisado por pares

Serum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy

2008; Oxford University Press; Volume: 23; Issue: 6 Linguagem: Inglês

10.1093/ndt/gfm913

ISSN

1460-2385

Autores

Sachiko Shimozato, Yosio Hiki, Hiroko Odani, Kazuo Takahashi, Koichiro Yamamoto, Shigeki Sugiyama,

Tópico(s)

Glycosylation and Glycoproteins Research

Resumo

Background. Immunoglobulin A nephropathy (IgAN) is characterized by an aberrant structure of O -glycans in the IgA1 hinge region. Recently, under-galactosylated IgA1 has been found to be increased in Caucasian IgAN patients. Thus, we examined this in Japanese IgAN patients.

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