Serum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy
2008; Oxford University Press; Volume: 23; Issue: 6 Linguagem: Inglês
10.1093/ndt/gfm913
ISSN1460-2385
AutoresSachiko Shimozato, Yosio Hiki, Hiroko Odani, Kazuo Takahashi, Koichiro Yamamoto, Shigeki Sugiyama,
Tópico(s)Glycosylation and Glycoproteins Research
ResumoBackground. Immunoglobulin A nephropathy (IgAN) is characterized by an aberrant structure of O -glycans in the IgA1 hinge region. Recently, under-galactosylated IgA1 has been found to be increased in Caucasian IgAN patients. Thus, we examined this in Japanese IgAN patients.
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