Artigo Acesso aberto Produção Nacional Revisado por pares

Utilization of acetonitrile and other aliphatic nitriles by a Candida famata strain

1996; Oxford University Press; Volume: 144; Issue: 1 Linguagem: Inglês

10.1111/j.1574-6968.1996.tb08510.x

ISSN

1574-6968

Autores

Valter R. Linardi, João C.T. Dias, Carlos Augusto Rosa,

Tópico(s)

Microbial Metabolic Engineering and Bioproduction

Resumo

A variant of a yeast strain identified as Candida famata isolated from gold mine effluent was able to grow on acetonitrile, acrylonitrile, butyronitrile, isobutyronitrile, methacrylnitrile, propionitrile, succinonitrile, valeronitrile, acetamide, isobutyamide, and succinamide as sole nitrogen source, after acclimatization. The yeast grew on acetonitrile and acetamide at concentrations up to 4%. The utilisation of acetonitrile and acetamide by the C. famata strain probably involves hydrolysis in a two-step reaction mediated by both inducible and intracellular nitrile hydratase and amidase.

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