Portal de Periódicos da CAPES

Neuroenergetics: Calling Upon Astrocytes to Satisfy Hungry Neurons

2004; SAGE Publishing; Volume: 10; Issue: 1 Linguagem: Inglês

10.1177/1073858403260159

1089-4098

Luc Pellerin, Pierre J. Magistretti,

Memory and Neural Mechanisms

Classical neuroenergetics states that glucose is the exclusive energy substrate of brain cells and its full oxidation provides all the necessary energy to support brain function. Recent data have revealed a more intricate picture in which astrocytes play a key role in supplying lactate as an additional energy substrate in register with glutamatergic activity.