Ethylene Glycol‐Protected Magnetic Nanoparticles for a Multiplexed Immunoassay in Human Plasma
2006; Wiley; Volume: 2; Issue: 4 Linguagem: Inglês
10.1002/smll.200500387
ISSN1613-6829
AutoresPo‐Chiao Lin, Po‐Hung Chou, Shu‐Hua Chen, Hsin‐Kai Liao, Kai‐Yi Wang, Yu‐Ju Chen, Chun‐Cheng Lin,
Tópico(s)Advanced Biosensing Techniques and Applications
ResumoSmallVolume 2, Issue 4 p. 485-489 Communication Ethylene Glycol-Protected Magnetic Nanoparticles for a Multiplexed Immunoassay in Human Plasma† Po-Chiao Lin, Po-Chiao Lin Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007 Chemical Biology and Molecular Biophysics, Taiwan International, Graduate Program, Academia Sinica, Taipei, Taiwan Department of Chemistry, National Tsing Hua University, Hsinchu, TaiwanSearch for more papers by this authorPo-Hung Chou, Po-Hung Chou Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorShu-Hua Chen, Shu-Hua Chen Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorHsin-Kai Liao, Hsin-Kai Liao Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorKai-Yi Wang, Kai-Yi Wang Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorYu-Ju Chen Dr., Yu-Ju Chen Dr. [email protected] Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007 Chemical Biology and Molecular Biophysics, Taiwan International, Graduate Program, Academia Sinica, Taipei, Taiwan Department of Chemistry, National Tsing Hua University, Hsinchu, TaiwanSearch for more papers by this authorChun-Cheng Lin Dr., Chun-Cheng Lin Dr. [email protected] Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007 Chemical Biology and Molecular Biophysics, Taiwan International, Graduate Program, Academia Sinica, Taipei, Taiwan Department of Chemistry, National Tsing Hua University, Hsinchu, TaiwanSearch for more papers by this author Po-Chiao Lin, Po-Chiao Lin Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007 Chemical Biology and Molecular Biophysics, Taiwan International, Graduate Program, Academia Sinica, Taipei, Taiwan Department of Chemistry, National Tsing Hua University, Hsinchu, TaiwanSearch for more papers by this authorPo-Hung Chou, Po-Hung Chou Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorShu-Hua Chen, Shu-Hua Chen Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorHsin-Kai Liao, Hsin-Kai Liao Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorKai-Yi Wang, Kai-Yi Wang Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007Search for more papers by this authorYu-Ju Chen Dr., Yu-Ju Chen Dr. [email protected] Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007 Chemical Biology and Molecular Biophysics, Taiwan International, Graduate Program, Academia Sinica, Taipei, Taiwan Department of Chemistry, National Tsing Hua University, Hsinchu, TaiwanSearch for more papers by this authorChun-Cheng Lin Dr., Chun-Cheng Lin Dr. [email protected] Institute of Chemistry and Genomic Research Center, Academia Sinica, Sec.2, Academia Rd. Taipei, 115, Taiwan, Fax: (+886) 2-2783-5007 Chemical Biology and Molecular Biophysics, Taiwan International, Graduate Program, Academia Sinica, Taipei, Taiwan Department of Chemistry, National Tsing Hua University, Hsinchu, TaiwanSearch for more papers by this author First published: 01 March 2006 https://doi.org/10.1002/smll.200500387Citations: 133 † This work was supported by the National Science and Technology Program for Nanoscience and Nanotechnology of Academia Sinica and the National Science Council, Taiwan. We also thank C. Y. Chen for assisting in the preparation of the manuscript. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract An attractive technique: Methoxyethyl-terminated ethylene glycol-protected antibody-conjugated magnetic nanoparticles (as depicted in the image) are demonstrated to act as specific affinity nanoprobes for the multiplexed detection of target proteins in human plasma and are excellent candidates for future clinical nanodiagnostics. Supporting Information Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2296/2006/z500387_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. References 1 Immunodiagnostics (Ed.: ), Oxford University Press, New York, 1994, pp. 1–43. 2 Immunoassays (Ed.: ), Oxford University Press, New York, 2000, pp. 1–14. 3 3aL. R. Nathaniel, C. A. Mirkin, Chem. Rev. 2005, 105, 1547–1562; 3bE. Katz, I. Willner, Angew. Chem. 2004, 116, 6166–6232; Angew. Chem. Int. Ed. 2004, 43, 6042–6108; 3cJ. Wang, Small 2005, 1, 1036–1043. 4W. J. Parak, D. Gerion, T. Pellegrino, D. Zanchet, C. Micheel, S. C. Williams, R. Boudreau, M. A. L. Gros, C. A. Larabell, A. P. Alivisatos, Nanotechnology 2003, 14, 15–27. 5 5aC. Xu, K. Xu, H. Gu, X. Zhong, Z. Guo, R. Zheng, X. Zhang, B. Xu, J. Am. Chem. Soc. 2004, 126, 3392–3393; 5bH. Gu, P. L. Ho, K. W. Tsang, L. Wang, B. Xu, J. Am. Chem. Soc. 2003, 125, 15702–15703. 6N. Tang, P. Toronatore, S. R. Weinberger, Mass Spectrom. Rev. 2004, 23, 34–44. 7 7aC.-C. Lin, Y.-C. Yeh, C.-Y. Yang, C.-L. Chen, C.-F. Chen, C.-C. Chen, Y.-C. Wu, J. Am. Chem. Soc. 2002, 124, 3508–3509; 7bC.-C. Lin, Y.-C. Yeh, G.-F. Chen, C.-Y. Yang, Y.-C. Chen, Y.-C. Wu, C.-C. Chen, Chem. Commun. 2003, 2920–2921; 7cY.-J. Chen, S.-H. Chen, Y.-Y. Chien, Y.-W. Chang, H.-K. Liao, C.-Y. Chang, M.-D. Jan, K.-T. Wang, C.-C. Lin, ChemBioChem 2005, 6, 1169–1173. 8P.-H. Chou, S. H. Chen, H.-K. Liao, P.-C. Lin, G.-R. Her, A. C.-Y. Lai, J.-H. Chen, C.-C. Lin, Y.-J. Chen, Anal. Chem. 2005, 77, 5990–5997. 9Y. S. Kang, S. Risbud, J. F. Rabolt, P. Stroeve, Chem. Mater. 1996, 8, 2209–2211. 10X. Liu, Z. Ma, J. Xing, H. Liu, J. Magn. Magn. Mater. 2004, 270, 1–6. 11J. M. Perez, F. J. Saeki, Y. Simeone, L. Josephson, R. Weissleder, J. Am. Chem. Soc. 2003, 125, 10192–10193. 12M. B. Pepys, J. Herbert, W. L. Hutchinson, G. A. Tennent, H. J. Lachmann, J. R. Gallimorem, L. B. Lovat, T. Bartfai, A. Alanine, C. Hertel, T. Hoffmann, R. Jakob-Roeten, R. D. Norcross, J. A. Kemp, K. Yamaura, M. Suzuki, G. W. Taylor, S. Murray, D. Thompson, A. Purvis, S. Kolstoe, S. P. Wood, P. N. Hawkins, Nature 2002, 417, 254–259. 13U. A. Kiernan, D. Nedelkov, K. A. Tubbs, E. E. Niedekofler, R. W. Nelson, Proteomics 2004, 4, 1825–1829. 14TBS (Tris-buffered saline): 50 mM Tris-HCl, 0.85 % NaCl, pH 7.5. 15M. Zheng, X. Huang, J. Am. Chem. Soc. 2004, 126, 12047–12054. 16K. L. Dombi, N. Gresang, C. Richert, Synthesis 2002, 6, 816–824. 17H. Yu, J. W. Raymonda, T. M. McMahon, A. A. Campagnari, Biosens. Bioelectron. 2000, 14, 829–840. 18J. F. Peter, K. B. Tomer, Anal. Chem. 2001, 73, 4012–4019. 19 19aG. Berton, R. Cordiano, R. Palmier, S. Pianca, V. Pagliara, P. Palatini, Am. Heart J. 2003, 145, 1094–1101; 19bE. Kuhn, J. Wu, J. Karl, H. Liao, W. Zolg, B. Guild, Proteomics 2004, 4, 1175–1186. 20C. M. Uhlar, A. S. Whitehead, Eur. J. Biochem. 1999, 265, 501–523. 21 21aS. Solakidi, A. Dessypris, G. P. Stathopoulos, G. Androulakis, C. E. Sekeris, Clin. Biochem. 2004, 37, 56–60; 21bJ. S. Jang, H. Y. Chao, Y. J. Lee, W. S. Ha, H. W. Kim, Oncol. Res. 2004, 14, 491–499. Citing Literature Volume2, Issue4April 2006Pages 485-489 ReferencesRelatedInformation
Referência(s)