Regulation of Autoimmune Disease Physiological and Therapeutic
1986; Wiley; Volume: 94; Issue: 1 Linguagem: Inglês
10.1111/j.1600-065x.1986.tb01161.x
ISSN1600-065X
Autores Tópico(s)Immune Cell Function and Interaction
ResumoImmunological ReviewsVolume 94, Issue 1 p. 5-21 Regulation of Autoimmune Disease Physiological and Therapeutic Irun R. Cohen, Irun R. Cohen Department of Cell Biology, The Weizmann Institute of Science, Rehovot, 76100, Israel.Search for more papers by this author Irun R. Cohen, Irun R. Cohen Department of Cell Biology, The Weizmann Institute of Science, Rehovot, 76100, Israel.Search for more papers by this author First published: December 1986 https://doi.org/10.1111/j.1600-065X.1986.tb01161.xCitations: 149AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Ben-Nun, A. & Cohen, I. R. (1981) Vaccination against autoimmune encephalomyelitis (EAE): attenuated autoimmune T lymphocytes confer resistance to induction of active EAE but not to EAE mediated by the intact T lymphocyte line. Eur. J. Immunol. 11, 949. Ben-Nun, A. & Cohen, I. R. (1982a) Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines. Process of selection of lines and characterization of the cells. J. Immunol. 129, 303. Ben-Nun, A. & Cohen, I. R. (1982b) Spontaneous remission and acquired resistance to autoimmune encephalomyelitis (EAE) are associated with suppression of T cell reactivity: Suppressed EAE effector T cells recovered as T cell lines. J. Immunol. 128, 1450. Ben-Nun, A., Eisenstein, S. & Cohen, I. R. (1982) Experimental autoimmune encephalomyelitis (EAE) in genetically resistant rats: PVG rats resist active induction of EAE but are susceptible to and can generate EAE effector T cell lines. J. Immunol. 129, 918. Ben-Nun, A., Wekerele, H. & Cohen, I. R. (1981a) The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur. J. Immunol. 11, 195. Ben-Nun, A., Wekerle, H. & Cohen, I. R. (1981b) Vaccination against autoimmune encephalomyelitis with T lymphocyte line cells reactive against myelin basic protein. Nature 292, 60. Beraud, E., Reshef, T., Vandenbark, A., Offner, H., Fritz, R., Chou, C.-H. J., Bernard, D. & Cohen, I. R. (1986) Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: Genotype of antigen presenting cells influences immunodominant epitope of basic protein. J. Immunol. 136, 511. Burnet, F. M. (1959) The Clonal Selection Theory of Acquired Immunity. Nashville , Vanderbilt University Press. Cohen, I. R. (1984a) Autoimmunity: Physiological and pernicious. Adv. Int. Med. 29, 147. Cohen, I. R. (1984b) Prospects for treatment of immunological diseases. In: Clinics in Immunology and Allergy, Vol. 4: No 3, eds. J. J. Rood, R. R. P. Vries & W. P. Saunders, p. 593. W. B. Saunders, London . Cohen, I. R. (1985) Experimental autoimmune encephalomyelitis: Pathogenesis and prevention. In: Immunoregulatory Processes in Multiple Sclerosis and Experimental Allergic Encephalomyelitis, Vol. 7, eds. A. A. Vandenbark & J. C. M. Raus, p. 91. Elsevier Press, Amsterdam . Cohen, I. R., Elias, D., Maron, R. & Shechter, Y. (1984a) Immunization to insulin generates anti-idiotypes that behave as antibodies to the insulin hormone receptor and cause diabetes mellitus. In: Idiotypy, eds. H. Kohler, J. Urbain & P. A. Cazenave, Vol. 20, p. 385. Academic Press, New York . Cohen, I. R., Ehas, D., Maron, R. & Shechter, Y. (1984b) Immunization to insulin generates anti-idiotypes that behave as antibodies to the insulin hormone receptor and cause diabetes mellitus. In: Idiotypy in Biology and Medicine, Vol. 20, p. 385. Cohen, I. R., Holoshitz, J., van Eden, W. & Frenkel, A. (1985) T lymphocyte clones illuminate pathogenesis and effect therapy of experimental arthritis. Arth. Rheum. 28, 841. Cohen, I. R. & Wekerle, H. (1977) Autoimmunity, self-recognition, and blocking factors. In: Autoimmunity. Genetic, Immunologic, Virologic, and Clinical Aspects, ed. N Talal., p. 231. Academic Press, New York . M. O. Dayhoff, ed. (1972) Atlas of Protein Sequence and Structure, pp. D186-D187. Natl. Biomed Res. Found., Washington , D. C. . Elias, D., Cohen, I. R., Shechter, Y., Spirer, Z. & Golander, A. Antibodies to the insulin receptor and anti-idiotypic antibodies to insulin in a child with hypoglycemia. (Submitted). Elias, D., Maron, R., Cohen, I. R. & Shechter, Y. (1984) Mouse antibodies to the insulin receptor developing spontaneously as anti-idiotypes. II. Effects on glucose homeostasis and the insulin receptor. J. Biol. Chem. 29, 6416. Guilbert, B., Dighiero, G. & Avrameas, S. (1982) Naturally occurring antibodies against nine common antigens in normal humans. I. Detection, isolation, and characterization. J. Immunol. 28, 2779. Holoshitz, I., Klajman, A., Druker, I., Lapidot, Z., Yaretzky, A., Frenkel, A., van Eden, W. & Cohen, I. R. (1986) T lymphocytes of rheumatoid arthritis patients show augmented reactivity to a fraction of mycobacteria cross-reactive with cartilage. Lancet II, 305. Holoshitz, J. Frenkel, A., Ben-Nun, A. & Cohen, I. R. (1983a) Autoimmune EAE mediated or prevented by T lymphocyte lines as directed against diverse antigenic determinants of myehn basic protein. Vaccination is determinant specific. J. Immunol. 131, 2810. Holoshitz, J., Matitiau, A. & Cohen, I. R. (1984a) Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II. J. Clin. Invest. 73, 211. Holoshitz, J., Matitiau, A. & Cohen, I. R. (1985) Role of the thymus in induction and transfer of vaccination against adjuvant arthritis with a T lymphocyte line in rats. J. Clin. Invest. 75, 472. Holoshitz, J., Naparstek, A., Ben-Nun, A., Marquardt, P. & Cohen, I. R. (1984b) T lymphocyte lines induce autoimmune encephalomyelitis, delayed hypersensitivity and bystander encephalitis or arthritis. Eur. J. Immunol. 14, 729. Holoshitz, J., Naparstek, Y., Ben-Nun, A. & Cohen, I. R. (1983b). Lines of T lymphocytes mediate or vaccinate against autoimmune arthritis. Science. 219, 56. Jerne, N. K. (1974) Towards a network theory of the immune system. Ann. Immunol. (Paris) 124C, 373. Leder, P. (1982) The genetics of antibody diversity. Sci. Am. 246, 72. Lider, O., Shinitzky, M. & Cohen, I. R. (1986) Vaccination against experimental autoimmune diseases using T lymphocytes treated with hydrostatic pressure. Ann. N.Y. Acad. Sci. USA (in press). Maron, R. & Cohen, I. R. (1980) A H-2K mutation controls immune response phenotype of autoimmune thyroiditis. Critical expression of mutant gene product in both thymus and thyroid glands. J. Exp. Med. 152, 115. Maron, R., Zerubavel, R., Friedman, A. & Cohen, I. R. (1983) T lymphocyte line specific for thyroglobulin produces or vaccinates against autoimmune thyroiditis in mice. J. Immunol. 131, 2316. Naparstek, Y., Ben-Nun, A., Holoshitz, J., Reshef, T., Frenkel, A., Rosenberg, M. & Cohen, I. R. (1983) T lymphocyte lines producing or vaccinating against autoimmune encephalomyelitis (EAE): Functional activation induces PNA receptors and accumulation in the brain and thymus of line cells. Eur. J. Immunol. 13, 418. Naparstek, Y., Cohen, I. R., Fuks, Z. & Vlodavsky, I. (1984) Activated T lymphocytes produce a matrix degrading heparin sulphate endoglycosidase. Nature 310, 241. Naparstek, Y., Holoshitz, J., Eisenstein, S., Reshef, T., Rappaport, S., Chemke, J., Ben-Nun, A. & Cohen, I. R. (1982) Effector T lymphocyte line cells migrate to the thymus and persist there. Nature 300, 262. Pearson, C. M. (1956) Development of arthritis, periarthritis and periostitis in rats given adjuvant. Proc. Soc. Exp. Biol. Med. 91, 95. Pearson, C. M. (1964) Experimental models in rheumatoid arthritis. Arth. Rheum. 7, 80. Reichert L., Or, A. & Shinitzky, M. (1986) Promotion of tumor immunogenicity in EL4 cells subjected to hydrostatic pressure. Cancer Immunol. Immunother. 22, 119. Shechter, Y., Elias, D., Maron, R. & Cohen, I. R. (1984) Mouse antibodies to the insulin receptor developing spontaneously as anti-idiotypes. I. Characterization of the antibodies. J. Biol. Chem. 259, 6411. Shechter, Y., Maron, R., Elias, D. & Cohen, I. R. (1982) Autoantibodies to the insulin receptor spontaneously arise as anti-idiotypes in mice immunized with insulin. Science 216, 542. Shinitzky, M. (1984) Membrane fluidity in malignancy - adversative and recuperative. Biochim. Biophys. Acta 738, 251. Smith, L. F. (1972) Amino acid sequences of insulins. Diabetes 21, Suppl. 2, 457. Svet-Moldavsky, G. J., Svet-Moldavskaya, I. A. & Raffkina, L. I. (1959) Various types of acquired resistance to experimental "allergic" encephalomyelitis. Nature 184, 1552. Swanborg, R. H. (1975) Antigen-induced inhibition of experimental allergic encephalomyelitis. III. Localization of an inhibitory site distinct from the major encephalitogenic determinant of myelin basic protein. J. Immunol. 114, 191. Talmon, J., Ranghino, G., Yonath, A. & Cohen, I. R. (1983) Structural analysis of insulin determinants seen by T cells directed by H-2 genes. Immunogenetics 18, 79. van Eden, W., Holoshitz, J., Nevo, Z., Frenkel, A., Klajman, A. & Cohen, I. R. (1985) Arthritis induced by a T lymphocyte clone that responds to mycobacterium tuberculosis and to cartilage proteoglycans. Proc. Natl. Acad. Sci. USA 82, 5117. Vandenbark, A. A., Offner, H., Reshef, T., Fritz, R., Chou, C.-HJ. & Cohen, I. R. (1985) Specificity of T lymphocyte lines for peptides of myelin basic protein. J. Immunol. 135, 229. Yarom, Y., Naparstek, Y., Holoshitz, J., Ben-Nun, A. & Cohen, I. R. (1983) Immunospecific inhibition of nerve conduction in isolated rat optic nerve exerted by a line of T lymphocytes reactive to basic protein of myelin. Nature 303, 246. Citing Literature Volume94, Issue1December 1986Pages 5-21 ReferencesRelatedInformation
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