Enantio-controlled route to the furofuran lignans: the total synthesis of (–)-sesamolin, (–)-sesamin, and (–)-acuminatolide

1988; Royal Society of Chemistry; Issue: 3 Linguagem: Inglês

10.1039/c39880000189

ISSN

2050-5639

Autores

Seiichi Takano, Takehiko Ohkawa, Tamori Shun'ichi, Shigeki Satoh, Kunio Ogasawara,

Tópico(s)

Coenzyme Q10 studies and effects

Resumo

The first enantio-controlled route to the furofuran lignans, (–)-sesamolin, (–)-sesamolin, and (–)-acuminatolide, has been developed starting from diethyl L-tartrate by employing an intramolecular hetero-Diels–Alder reaction as the key step.

Referência(s)