Artigo Acesso aberto Revisado por pares

Synthesis and Cytotoxic Activity of pyridazino[1′,6′:1,2]pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents

2002; Elsevier BV; Volume: 12; Issue: 18 Linguagem: Inglês

10.1016/s0960-894x(02)00472-9

ISSN

1464-3405

Autores

Alberto Fontana, Enrique J. Benito, Marie Martin, Nuria Sánchez-López, Ramón Alajarı́n, Juan J. Vaquero, Julio Álvarez‐Buílla, Stéphanie Lambel-Giraudet, Stéphane Léonce, Alain St. Pierre, Daniel H. Caignard,

Tópico(s)

Synthesis and Reactivity of Heterocycles

Resumo

Several new pyridazino[1′,6′:1,2]pyrido[3,4-b]indol-5-inium derivatives were synthesised from β-carboline derivatives and their cytotoxic activity and effect on the cell cycle were evaluated against L1210 cancer cells.

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