Phototoxic and Photoallergic Reactions
2010; Wiley; Linguagem: Inglês
10.1007/978-3-642-03827-3_18
ISSN1600-0536
Autores Tópico(s)Photodynamic Therapy Research Studies
ResumoPhototoxic and photoallergic reactions represent skin reactions to the sun, in the presence of photoactive chemicals applied on the skin or taken systemically. They have a highly polymorphic clinical presentation – photocontact urticaria, eczema on sun-exposed areas sometimes with erythema multiforme, exaggerated sunburn, linear phytophotodermatitis, pseudoporphyria, photoonycholysis, dyschromia, and lupus erythematosus. Also, skin cancers are increasingly associated with exposure to photoactive chemicals. There is a geographical and timely variation in the responsible agents, but they are mostly furocumarins from plants, UV filters in sunscreens and cosmetics, and drugs (NSAIDs, antimicrobials, phenothiazines, amiodarone, etc.).
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