Cardiac AAV9-S100A1 Gene Therapy Rescues Post-Ischemic Heart Failure in a Preclinical Large Animal Model
2011; American Association for the Advancement of Science; Volume: 3; Issue: 92 Linguagem: Inglês
10.1126/scitranslmed.3002097
ISSN1946-6242
AutoresSven T. Pleger, Changguang Shan, Jan Ksienzyk, Raffi Bekeredjian, Peter Boekstegers, Rabea Hinkel, Stefanie Schinkel, Barbara Leuchs, Jochen Ludwig, Gang Qiu, Christophe Weber, Philip Raake, Walter J. Koch, Hugo A. Katus, Oliver J. Müller, Patrick Most,
Tópico(s)Cardiovascular Effects of Exercise
ResumoA protein that regulates cellular calcium, delivered percutaneously to the heart by gene therapy, improves cardiac function in pigs with heart failure and may also be effective in humans.
Referência(s)