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Chiral Nanoporous Metal‐Organic Frameworks with High Porosity as Materials for Drug Delivery

2011; Volume: 23; Issue: 47 Linguagem: Inglês

10.1002/adma.201102538

1521-4095

Chunyi Sun, Chao Qin, Chun‐Gang Wang, Zhong‐Min Su, Shuang Wang, Xinlong Wang, Guang‐Sheng Yang, Kui‐Zhan Shao, Ya‐Qian Lan, En‐Bo Wang,

Dendrimers and Hyperbranched Polymers

A chiral nanoporous metal-organic framework (MOF) with high porosity is obtained based on nontoxic zinc and achiral hexadentate ligand. It shows high drug loading and slow release of the proportion of the loaded drug with a complete delivery time of about one week when used as a material for adsorption and delivery of anticancer 5-fluorouracil. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.