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Type VI secretion system regulation as a consequence of evolutionary pressure

2013; Microbiology Society; Volume: 62; Issue: 5 Linguagem: Inglês

10.1099/jmm.0.053983-0

1473-5644

Sarah T. Miyata, Verena Bachmann, Stefan Pukatzki,

Aquaculture disease management and microbiota

The type VI secretion system (T6SS) is a mechanism evolved by Gram-negative bacteria to negotiate interactions with eukaryotic and prokaryotic competitors. T6SSs are encoded by a diverse array of bacteria and include plant, animal, human and fish pathogens, as well as environmental isolates. As such, the regulatory mechanisms governing T6SS gene expression vary widely from species to species, and even from strain to strain within a given species. This review concentrates on the four bacterial genera that the majority of recent T6SS regulatory studies have been focused on: Vibrio, Pseudomonas, Burkholderia and Edwardsiella.