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Bacteria etiological agents causing lower respiratory tract infections in the western part of Nepal

2014; Thieme Medical Publishers (Germany); Volume: 06; Issue: 01 Linguagem: Inglês

10.4103/1947-489x.210353

1947-489X

Salman Khan, Priti Singh, Mukhtar Ansari, Kishor Gurung,

Nosocomial Infections in ICU

Objectives: Lower respiratory tract infections (LRTIs) are among the most common infectious disease. We determined the bacterial etiology of LRTIs among patients attending Nepalgunj Medical College teaching hospital in Banke, western Nepal. Materials and Methods: 426 specimens from patients with suspected LRTIs attending out-patients and in-patients departments were studied. The specimens were collected and processed according to standard methodology in the Central Laboratory of Microbiology at Nepalgunj Medical College and Teaching Hospital, Banke, Nepal during the period of January to December 2012. Results: Respiratory pathogens were recovered from 210 cases (49.3%). Bacteria were more commonly recovered from endotracheal secretions (86 cases; 41%) than in sputum (82 cases; 39%) and bronchial washing (42 cases, 20%). In168 cases, growth was monomicrobial while the rest was mixed growth. Gram-negative bacteria were isolated in 246 cases (80.9%) and Gram-positive bacteria in 58 cases (19.1%). Among the Gram-positive organisms isolated, Streptococcus pneumoniae (30, 51.7%) was the most predominant pathogen followed by Staphylococcus aureus (28, 48.3%) and in Gram-negative organisms isolated, Pseudomonas aeruginosa (116, 47.2%) was most predominant pathogen followed by Haemophilus influenzae (68, 27.6%), Klebsiella pneumoniae (36, 14.6%) and Escherichia coli (26, 10.6%). Conclusions: Respectively, Pseudomonas aeruginosa and Streptococcus pnemoniae were the most common Gram negative and Gram-positive bacterial isolates recovered from LRTIs. Close monitoring and surveillance of these pathogens is urged.