Artigo Acesso aberto Produção Nacional Revisado por pares

Demyelinating disease in patients with myasthenia gravis

2008; Thieme Medical Publishers (Germany); Volume: 66; Issue: 1 Linguagem: Inglês

10.1590/s0004-282x2008000100002

ISSN

1678-4227

Autores

Denis Bernardi Bichuetti, Tatiane Martins de Barros, Enedina Maria Lobato de Oliveira, Marcelo Annes, Alberto Alain Gabbai,

Tópico(s)

Parkinson's Disease and Spinal Disorders

Resumo

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.

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