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A possible rat model for non‐alcoholic steatohepatitis: Histological findings in SHR/NDmcr‐cp rats

2008; Wiley; Volume: 38; Issue: 7 Linguagem: Inglês

10.1111/j.1872-034x.2008.00342.x

1872-034X

Shigeko Kato, Katsuhisa Omagari, Koichi Tsuneyama, Eri Fukazawa, Hiroe Tsukuda, Chisato Inohara, Yu Kuroda, Keiko Shiraishi, Masatoshi Mune,

Peroxisome Proliferator-Activated Receptors

Hepatology ResearchVolume 38, Issue 7 p. 743-744 A possible rat model for non-alcoholic steatohepatitis: Histological findings in SHR/NDmcr-cp rats Shigeko Kato, Shigeko Kato Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorKatsuhisa Omagari, Corresponding Author Katsuhisa Omagari Department of Nutrition, University of Nagasaki, Nagasaki,Prof Katsuhisa Omagari, Department of Nutrition, University of Nagasaki, 1-1-1 Manabino, Nagayo-cho, Nagasaki 851-2195, Japan. Email: [email protected]Search for more papers by this authorKoichi Tsuneyama, Koichi Tsuneyama Department of Diagnostic Pathology, University of Toyama, Toyama, andSearch for more papers by this authorEri Fukazawa, Eri Fukazawa Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorHiroe Tsukuda, Hiroe Tsukuda Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorChisato Inohara, Chisato Inohara Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorYu Kuroda, Yu Kuroda Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorKeiko Shiraishi, Keiko Shiraishi Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorMasatoshi Mune, Masatoshi Mune Ryoshukai Takaishi Fujii Hospital, Osaka, JapanSearch for more papers by this author Shigeko Kato, Shigeko Kato Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorKatsuhisa Omagari, Corresponding Author Katsuhisa Omagari Department of Nutrition, University of Nagasaki, Nagasaki,Prof Katsuhisa Omagari, Department of Nutrition, University of Nagasaki, 1-1-1 Manabino, Nagayo-cho, Nagasaki 851-2195, Japan. Email: [email protected]Search for more papers by this authorKoichi Tsuneyama, Koichi Tsuneyama Department of Diagnostic Pathology, University of Toyama, Toyama, andSearch for more papers by this authorEri Fukazawa, Eri Fukazawa Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorHiroe Tsukuda, Hiroe Tsukuda Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorChisato Inohara, Chisato Inohara Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorYu Kuroda, Yu Kuroda Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorKeiko Shiraishi, Keiko Shiraishi Department of Nutrition, University of Nagasaki, Nagasaki,Search for more papers by this authorMasatoshi Mune, Masatoshi Mune Ryoshukai Takaishi Fujii Hospital, Osaka, JapanSearch for more papers by this author First published: 25 March 2008 https://doi.org/10.1111/j.1872-034X.2008.00342.xCitations: 3Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1 Marchesini G, Bugianesi E, Forlani G et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003; 37: 917–23. 2 Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology 2003; 37: 1202–19. 3 Weltman MD, Farrell GC, Liddle C. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. Gastroenterology 1996; 111: 1645–53. 4 Qi NR, Wang J, Zidek V et al. A new transgenic rat model of hepatic steatosis and the metabolic syndrome. Hypertension 2005; 45: 1004–11. 5 Nangaku M, Izuhara Y, Usuda N et al. In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy. Nephrol Dial Transplant 2005; 20: 2661–9. 6 Nangaku M, Miyata T, Sada T et al. Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model. J Am Soc Nephrol 2003; 14: 1212–22. 7 Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993; 123: 1939–51. 8 Hiraoka-Yamamoto J, Ikeda K, Yamori Y. Obese and hypertensive SHR/NDmcr-cp rats -a model of metabolic syndrome. Adiposcience 2005; 2: 243–8. (In Japanese with English abstract). 9 Kleiner DE, Brunt EM, Van Natta M et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313–21. 10 Kainuma M, Fujimoto M, Sekiya N et al. Cholesterol-fed rabbit as a unique model of nonalcoholic, nonobese, non-insulin-resistant fatty liver disease with characteristic fibrosis. J Gastroenterol 2006; 41: 971–80. Citing Literature Volume38, Issue7July 2008Pages 743-744 ReferencesRelatedInformation