In-vitro susceptibility of thirty strains of Haemophilus ducreyi to several antibiotics including six cephalosporins
1983; Oxford University Press; Volume: 11; Issue: 3 Linguagem: Inglês
10.1093/jac/11.3.271
ISSN1460-2091
AutoresM.-J. Sanson-Le Pors, I Casin, M Ortenberg, Y Pérol,
Tópico(s)Pneumocystis jirovecii pneumonia detection and treatment
ResumoWe have studied the in-vitro susceptibility of 30 strains of Haemophilus ducreyi to 22 antibacterial agents. Twenty-seven strains produced a η-lactamase that had an isoelectric point similar to the isoelectric point of the TEM 1 type β-lactamase produced by pSF 2124. Except for cefamandole, the 30 strains had similar susceptibilities to the different cephalosporins, cefotaxime being the most active compound. Twenty-two isolates were resistant to tetracycline and doxycycline; minimal inhibitory concentration (MIC) of minocycline was 4 mg/1 for all the strains. One isolate was resistant to chloramphenicol (MIC= 16mg/l). All strains were relatively resistant to colistin and nalidixic acid, and susceptible to streptomycin, kanamycin, gentamicin, erythromycin, rifampicin and vancomycin.
Referência(s)