The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
2011; American Association for the Advancement of Science; Volume: 332; Issue: 6035 Linguagem: Inglês
10.1126/science.1199498
ISSN1095-9203
AutoresPeggy P. Hsu, Seong A. Kang, Jonathan Rameseder, Yi Zhang, Kathleen Ottina, Daniel Lim, Timothy R. Peterson, Yongmun Choi, Nathanael S. Gray, Michael B. Yaffe, Jarrod A. Marto, David M. Sabatini,
Tópico(s)Protein Kinase Regulation and GTPase Signaling
ResumoA search for substrates of a growth-promoting kinase revealed a regulatory feedback loop involved in tumor suppression.
Referência(s)