Artigo Acesso aberto Revisado por pares

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

2011; American Association for the Advancement of Science; Volume: 332; Issue: 6035 Linguagem: Inglês

10.1126/science.1199498

ISSN

1095-9203

Autores

Peggy P. Hsu, Seong A. Kang, Jonathan Rameseder, Yi Zhang, Kathleen Ottina, Daniel Lim, Timothy R. Peterson, Yongmun Choi, Nathanael S. Gray, Michael B. Yaffe, Jarrod A. Marto, David M. Sabatini,

Tópico(s)

Protein Kinase Regulation and GTPase Signaling

Resumo

A search for substrates of a growth-promoting kinase revealed a regulatory feedback loop involved in tumor suppression.

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