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Point-of-care coagulation management in intensive care medicine

2013; BioMed Central; Volume: 17; Issue: 2 Linguagem: Inglês

10.1186/cc12527

1466-609X

Patrick Meybohm, Kai Zacharowski, Christian Weber,

Sepsis Diagnosis and Treatment

Coagulopathy in critically ill patients is common and of multifactorial origin [1]. Coagulopathy-associated risk of bleeding and the use of allogeneic blood products are independent risk factors for morbidity and mortality [2, 3]. Therefore, prompt and correct identification of the underlying causes of these coagulation abnormalities is required, since each coagulation abnormality necessitates very different therapeutic management strategies. Standard laboratory tests of blood coagulation yield only partial diagnostic information, and important coagulation defects, e.g., reduced clot stability, platelet dysfunction, or hyperfibrinolysis, remain undetected.