Metabotype analysis for personalized biology: a new bioanalytical territory for high-resolution MS
2013; Future Science Ltd; Volume: 5; Issue: 10 Linguagem: Inglês
10.4155/bio.13.79
ISSN1757-6199
AutoresBertrand Rochat, Amélie Favre, Sottas Pierre-Edouard,
Tópico(s)Advanced Proteomics Techniques and Applications
ResumoBioanalysisVol. 5, No. 10 EditorialMetabotype analysis for personalized biology: a new bioanalytical territory for high-resolution MSRochat Bertrand, Favre Amélie & Sottas Pierre-EdouardRochat Bertrand* Author for correspondenceQuantitative Mass Spectrometry Facility, University of Lausanne, CHUV, CH-1011 Lausanne, Switzerland. , Favre AmélieQuantitative Mass Spectrometry Facility, University of Lausanne, Lausanne, Switzerland & Sottas Pierre-EdouardBioKaizen, Monthey, SwitzerlandPublished Online:30 May 2013https://doi.org/10.4155/bio.13.79AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: biological passportLC–HRMSmetabolomicsmetabotypingpersonalized medicineReferences1 Psychogios N, Hau DD, Peng J et al. The human serum metabolome. PLoS One6,e16957 (2011).Crossref, Medline, CAS, Google Scholar2 Joyner MJ, Pedersen BK. Ten questions about systems biology. J. Physiol.589,1017–30 (2011).Crossref, Medline, CAS, Google Scholar3 Henry H, Sobhi HR, Scheibner O, Bromirski M, Nimkar SB, Rochat B. Comparison between a high-resolution single-stage Orbitrap and a triple quadrupole mass spectrometer for quantitative analyses of drugs. Rapid Commun. Mass Spectrom.26,499–509 (2012).Crossref, Medline, CAS, Google Scholar4 Ramanathan R, Korfmacher W. The emergence of high-resolution MS as the premier analytical tool in the pharmaceutical bioanalysis arena. Bioanalysis4,467–469 (2012).Link, CAS, Google Scholar5 Rochat B, Kottelat E, McMullen J. The future key role of LC–high-resolution-MS analyses in clinical laboratories: a focus on quantification. Bioanalysis4,2939–2958 (2012).Link, CAS, Google Scholar6 Dunn WB, Broadhurst D, Begley P et al. Human serum metabolome (HUSERMET) consortium. Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry. Nat. Protoc.6,1060–1083 (2011).Crossref, Medline, CAS, Google Scholar7 Yuan M, Breitkopf SB, Yang X, Asara JM. A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue. Nat. Protoc.7,872–881 (2012).Crossref, Medline, CAS, Google Scholar8 Vuckovic D. Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry. Anal. Bioanal. Chem.403,1523–1548 (2012).Crossref, Medline, CAS, Google Scholar9 Gika HG, Theodoridis GA, Vrhovsek U, Mattivi F. Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatography–tandem mass spectrometry. J. Chromatogr. A1259,121–127 (2012).Crossref, Medline, CAS, Google Scholar10 Dumlao DS, Buczynski MW, Norris PC, Harkewicz R, Dennis EA. High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines. Biochim. Biophys. Acta.1811,724–736 (2011).Crossref, Medline, CAS, Google Scholar11 Nicholls AW. Realising the potential of metabolomics. Bioanalysis4,2195–2197 (2012).Link, CAS, Google Scholar12 Dunn WB, Broadhurst D, Brown M et al. Metabolic profiling of serum using ultra performance liquid chromatography and the LTQ-Orbitrap mass spectrometry system. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.871,288–98 (2008).Crossref, Medline, CAS, Google Scholar Nicholson G, Rantalainen M, Maher AD et al. Human metabolic profiles are stably controlled by genetic and environmental variation. Mol. Syst. Biol.7,525 (2011).Crossref, Medline, CAS, Google Scholar14 Plebani M, Lippi G. Personalized (laboratory) medicine: a bridge to the future. Clin. Chem. Lab. Med.6,1–4 (2013).Crossref, Google Scholar15 Sottas PE, Kapke GF, Vesterqvist O, Leroux JM. Patient-specific measures of a biomarker for the generation of individual reference intervals: hemoglobin as example. Transl. Res.158,360–368 (2011).Crossref, Medline, CAS, Google Scholar16 Sottas PE, Vernec A. Current implementation and future of the Athlete Biological Passport. Bioanalysis4,1645–1652 (2012).Link, CAS, Google Scholar17 Sottas PE, Kapke GF, Leroux JM. Adaptive bayesian approach to clinical trial renal impairment biomarker signal from urea and creatinine. Int. J. Biol. Sci.9,156–163 (2013).Crossref, Medline, CAS, Google Scholar18 Adamski J, Suhre K. Metabolomics platforms for genome wide association studies-linking the genome to the metabolome. Curr. Opin. Biotechnol.24,39–47 (2013).Crossref, Medline, CAS, Google Scholar19 Suhre K, Shin SY, Petersen AK et al. Human metabolic individuality in biomedical and pharmaceutical research. Nature477,54–60 (2011).Crossref, Medline, CAS, Google Scholar20 Bellcross CA, Page PZ, Meaney-Delman D. Direct-to-consumer personal genome testing and cancer risk prediction. Cancer J.18,293–302 (2012).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetailsCited ByValidation of the Mass-Extraction-Window for Quantitative Methods Using Liquid Chromatography High Resolution Mass Spectrometry23 February 2016 | Analytical Chemistry, Vol. 88, No. 6Validation of hepcidin quantification in plasma using LC–HRMS and discovery of a new hepcidin isoformBertrand Rochat, Davide Peduzzi, Justin McMullen, Amélie Favre, Emmanuel Kottelat, Bernard Favrat, Jean-Daniel Tissot, Anne Angelillo-Scherrer, Maciej Bromirski & Sophie Waldvogel18 October 2013 | Bioanalysis, Vol. 5, No. 20Bioanalysis annual round-up: The Bioanalysis Editorial team is delighted to welcome you to this mid-year round-up23 September 2013 | Bioanalysis, Vol. 5, No. 18Preface to the 2013 Special Focus Issue of Bioanalysis on high-resolution MSWalter Korfmacher & Ragu Ramanathan30 May 2013 | Bioanalysis, Vol. 5, No. 10 Vol. 5, No. 10 STAY CONNECTED Metrics Downloaded 194 times History Published online 30 May 2013 Published in print May 2013 Information© Future Science LtdKeywordsbiological passportLC–HRMSmetabolomicsmetabotypingpersonalized medicineFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download
Referência(s)