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The Tortoiseshell Pattern in One or Both Sides of the Submandibular Glands in Mucosa-Associated Lymphoid Tissue Lymphoma Is Related to Chromosomal Aberrations and the Disease Extent

2010; Wiley; Volume: 29; Issue: 1 Linguagem: Inglês

10.7863/jum.2010.29.1.111

1550-9613

Satomi Asai, Kenji Okami, Naoya Nakamura, Yoshiaki Ogawa, Yoshihide Ohta, Yoko Ogase, Jin Gui-lan, Hiromichi Matsushita, Hayato Miyachi,

Ear and Head Tumors

Journal of Ultrasound in MedicineVolume 29, Issue 1 p. 111-115 Case Series The Tortoiseshell Pattern in One or Both Sides of the Submandibular Glands in Mucosa-Associated Lymphoid Tissue Lymphoma Is Related to Chromosomal Aberrations and the Disease Extent Satomi Asai MD, PhD, Corresponding Author Satomi Asai MD, PhD sa@is.icc.u-tokai.ac.jp Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanAddress correspondence to Satomi Asai, MD, PhD, Department of Laboratory Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.Search for more papers by this authorKenji Okami MD, PhD, Kenji Okami MD, PhD Department of Otolaryngology, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorNaoya Nakamura MD, PhD, Naoya Nakamura MD, PhD Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorYoshiaki Ogawa MD, PhD, Yoshiaki Ogawa MD, PhD Department of Internal Medicine, Section of Hematology, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorYoshihide Ohta DDS, PhD, Yoshihide Ohta DDS, PhD Department of Dentistry and Oral Surgery, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorYoko Ogase, Yoko Ogase Clinical Laboratory Center, Tokai University Hospital, Isehara, Kanagawa, JapanSearch for more papers by this authorGuilan Jin, Guilan Jin Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorHiromichi Matsushita MD, PhD, Hiromichi Matsushita MD, PhD Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorHayato Miyachi MD, PhD, Hayato Miyachi MD, PhD Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this author Satomi Asai MD, PhD, Corresponding Author Satomi Asai MD, PhD sa@is.icc.u-tokai.ac.jp Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanAddress correspondence to Satomi Asai, MD, PhD, Department of Laboratory Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.Search for more papers by this authorKenji Okami MD, PhD, Kenji Okami MD, PhD Department of Otolaryngology, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorNaoya Nakamura MD, PhD, Naoya Nakamura MD, PhD Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorYoshiaki Ogawa MD, PhD, Yoshiaki Ogawa MD, PhD Department of Internal Medicine, Section of Hematology, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorYoshihide Ohta DDS, PhD, Yoshihide Ohta DDS, PhD Department of Dentistry and Oral Surgery, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorYoko Ogase, Yoko Ogase Clinical Laboratory Center, Tokai University Hospital, Isehara, Kanagawa, JapanSearch for more papers by this authorGuilan Jin, Guilan Jin Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorHiromichi Matsushita MD, PhD, Hiromichi Matsushita MD, PhD Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this authorHayato Miyachi MD, PhD, Hayato Miyachi MD, PhD Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, JapanSearch for more papers by this author First published: 01 January 2010 https://doi.org/10.7863/jum.2010.29.1.111Citations: 11Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Objective. Lesions of mucosa-associated lymphoid tissue (MALT) lymphoma in the submandibular glands are localized or a part of systemic involvement in association with chromosomal aberrations. This series was undertaken to investigate the sonographic features of MALT lymphoma in the submandibular glands and their relationships with chromosomal aberrations and the disease extent. Methods. A total of 5 patients with MALT lymphoma without Sjögren syndrome in the submandibular glands were enrolled in this series. Patients underwent sonography of the submandibular glands with a high-resolution transducer before surgical biopsy of the main lesion. Sonographic characteristics of the lesions were described for their location, presence of a posterior echo, texture, and presence of an internal echo. Results. Sonography in all cases showed hypoechoic and solid masses with increased posterior echo enhancement. There was an arrangement of hypoechoic small compartments demarcated by hyperechoic contour lines, which had a tortoiseshell pattern. This pattern was classified into 2 types according to its location: a lesion in the right or left side and lesions in both sides of the submandibular glands, found in 3 and 2 patients, respectively. The latter 2 cases had chromosomal aberrations of t(11;18)(q23;q23) and t(12;18)(q22;q21), respectively, and were revealed as secondary organ involvement. Conclusions. The sonographic appearance of MALT lymphoma in the submandibular glands was characterized by the tortoiseshell pattern in both primary and secondary lesions. Detection of this pattern in both sides of the submandibular glands can be an indicator of chromosomal aberrations and systematic involvement of the disease. Citing Literature Volume29, Issue1January 2010Pages 111-115 RelatedInformation