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Bone Pain in Multiple Myeloma

1972; American Medical Association; Volume: 130; Issue: 1 Linguagem: Inglês

10.1001/archinte.1972.03650010041008

1538-3679

N. David Charkes,

Multiple Myeloma Research and Treatments

Five patients with multiple myeloma were studied by serial radioactive strontium 87m Sr citrate or carbonate bone scans over a period of one year. Severe and constant pain was associated with abnormalities on the scans; subsequent roentgenograms of these areas invariably showed vertebral collapse or infraction. On the other hand, old vertebral collapse, per se, did not give rise to bone pain. It is concluded that the cause of the bone pain in myeloma is infraction. Local treatment of such bones with radiation may prevent vertebral collapse and pathologic fracture.