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Cutaneous Anthrax Associated With Microangiopathic Hemolytic Anemia and Coagulopathy in a 7-Month-Old Infant

2002; American Medical Association; Volume: 287; Issue: 7 Linguagem: Inglês

10.1001/jama.287.7.869

1538-3598

Abigail Freedman, Olubunmi Afonja, Mary Wu Chang, Farzad Mostashari, Martin J. Blaser, Guillermo I. Pérez‐Pérez, Herb Lazarus, Robert G. Schacht, Jane Guttenberg, Michael Traister, William Borkowsky,

Rabies epidemiology and control

A 7-month-old infant with cutaneous anthrax developed severe systemic illness despite early treatment with antibiotics. The infant displayed severe microangiopathic hemolytic anemia with renal involvement, coagulopathy, and hyponatremia. These findings are unusual with cutaneous anthrax, but have been described in illness resulting from spider toxin and may delay correct diagnosis. The systemic manifestations of the disease persisted for nearly a month despite corticosteroid therapy, but resolved.