On the changes in glomeruli and arteries in inflammatory and arterio‐sclerotic kidney disease
1911; Volume: 16; Issue: 1 Linguagem: Inglês
10.1002/path.1700160126
ISSN1096-9896
Autores Tópico(s)Atherosclerosis and Cardiovascular Diseases
ResumoRECENT work has emphasised the importance of the changes in the arteries and glomeruli in the various forms of general disease of the kidney which are not associated with pyogenic or specific organisms.On the one band, the work of Jores and his school has again brought into prominence the view, which was originally formulated by Gull and Sutton, that certain forms of contracted kidney are due to primary changes in the small arteries; and on the other hand, the investigations of Lohlein in cases of acute nephritis have emphasised the importance of the glomerular changes which are associated with and differentiate the various forms that occur in this group.Professor Aschoff therefore suggested to me that an investigation of these points should be undertaken.I wish here to express my great indebtedness to him both for this suggestion and for the great help which he has given me throughout the research.I may say that his wide and intimate knowledge of the pathology of the kidney has alone made the investigation possible.This paper deals especially with the various forms of contracted kidney.It attempts also to trace tQe course of the glomerular changes in these diseases, and to estimitte the value of these changes for the classification of the various forms of kidney disease in harmony wilh their clinical manifestations.Th. reconciliation of the clinical and pathological conditions has, throughout, been the chief object of the research.The material examined has been selected from over two hundred consecutive post-mortems and from the museum specimens of Freiburgin-Breisgau.All kidneys showing contraction or signs of inflammation
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