Reactions with hydroxamoyl halides: Synthesis of several isoxazole, imidazo[1,2‐a]pyridine, imidazo[1,2‐a]pyrimidine and benz‐1,2,4‐triazine derivatives
1988; Wiley; Volume: 321; Issue: 12 Linguagem: Inglês
10.1002/ardp.19883211217
ISSN1521-4184
AutoresAbdou O. Abdelhamid, A. M. NEGM, Talaat M. S. Abdeen,
Tópico(s)Synthesis of heterocyclic compounds
ResumoAbstract Benzofuroylhydroxamoyl chloride ( 3 ) reacted with acrylonitrile, N‐tolyl‐maleimide and active methylene compounds to afford the isoxazoline 4 , the pyrrolidino[3,4‐d]isoxazoline 5 and the isoxazole derivatives 6,7 , respectively. Nitrosoimidazo[1,2‐a]pyridines 10 and the imidazo[1,2‐a]pyrimidine 12 were obtained by the reaction of 3 with 2‐aminopyridine and 2‐aminopyrimidine, respectively. 3 reacted also with o‐phenylenediamine and o‐aminothiophenol to give the dihydrobenztriazine 13 and the benzothiadiazine 15 , respectively.
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