Portal de Periódicos da CAPES

Cohort Profile: French hospital database on HIV (FHDH-ANRS CO4)

2014; Oxford University Press; Volume: 43; Issue: 5 Linguagem: Inglês

10.1093/ije/dyu002

1464-3685

Murielle Mary‐Krause, Sophie Grabar, Laurence Lièvre, Sophie Abgrall, E. Billaud, François Boué, L. Boyer, André Cabie, Laurent Cotte, P. de Truchis, Xavier Duval, Claudine Duvivier, P. Enel, Jacques Gasnault, C. Gaud, Jacques Gilquin, Marguerite Guiguet, Christine Katlama, Marie-Aude Khuong-Josses, Jean‐Marc Lacombe, Sylvie Lang, A.-S. Lascaux, O. Launay, Aba Mahamat, Sophie Matheron, Jean Luc Meynard, J. Pavie, F. Pilorge, L Piroth, Isabelle Poizot‐Martin, Valérie Potard, Christian Pradier, Jacques Reynes, É. Rouveix, Hana Selinger‐Leneman, Anne Simon, Pierre Tattevin, Hervé Tissot‐Dupont, Jean‐Paul Viard, N. Viget, Dominique Costagliola,

HIV/AIDS drug development and treatment

The French Hospital Database on HIV (FHDH) is a hospital-based multicentre open cohort with inclusions ongoing since 1989. The research objectives focus mainly on mid- and long-term clinical outcomes and therapeutic strategies, as well as severe AIDS and non-AIDS morbidities, and public health issues relative to HIV infection. FHDH also serves to describe HIV-infected patients receiving hospital care in France. FHDH includes data on more than 120 000 HIV-infected patients from 70 French general or university hospitals distributed throughout France. Patients are eligible for inclusion if they are infected by HIV-1 or HIV-2 and give their written informed consent. Standardized variables are collected at each outpatient visit or hospital admission during which a new clinical manifestation is diagnosed, a new treatment is prescribed or a change in biological markers is noted, and/or at least every 6 months. Since its inception, variables collected in FHDH include demographic characteristics, HIV-related biological markers, the date and type of AIDS and non AIDS-defining events, antiretroviral treatments and the date and causes of death, as reported in the medical records. Since 2005, data have also been collected on: co-infection with hepatitis B or C virus; alcohol and tobacco use; and non HIV-related biomarkers. Anyone can submit a research project by completing a standardized form available on the FHDH website (http://www.ccde.fr/_fold/fl-1385734776-429.pdf) or from the corresponding author, describing the context and objectives of the study. All projects are reviewed by the scientific committee.